Hammerhead ribozyme-based U-insertion and deletion RNA editing assays for multiplexing in HTS applications

Untranslatable mitochondrial transcripts in kinetoplastids are decrypted post-transcriptionally through an RNA editing process that entails uridine insertion/deletion. This unique stepwise process is mediated by the editosome, a multiprotein complex that is a validated drug target of considerable in...

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Detalles Bibliográficos
Autores principales: Rostamighadi, Mojtaba, Mehta, Vaibhav, Hassan Khan, Rufaida, Moses, Daniel, Salavati, Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2023
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891259/
https://www.ncbi.nlm.nih.gov/pubmed/36456183
http://dx.doi.org/10.1261/rna.079454.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891259/
https://www.ncbi.nlm.nih.gov/pubmed/36456183
http://dx.doi.org/10.1261/rna.079454.122

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