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Hammerhead ribozyme-based U-insertion and deletion RNA editing assays for multiplexing in HTS applications
Untranslatable mitochondrial transcripts in kinetoplastids are decrypted post-transcriptionally through an RNA editing process that entails uridine insertion/deletion. This unique stepwise process is mediated by the editosome, a multiprotein complex that is a validated drug target of considerable in...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891259/ https://www.ncbi.nlm.nih.gov/pubmed/36456183 http://dx.doi.org/10.1261/rna.079454.122 |