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Cancer-associated fibroblasts-derived exosomes from chemoresistant patients regulate cisplatin resistance and angiogenesis by delivering VEGFA in colorectal cancer

The purpose of this study was to investigate the effect of chemoresistant cancer-associated fibroblasts (R-CAFs) against cisplatin (DDP) on colorectal cancer (CRC) progression. First, clinical tissue samples of chemoresistant or chemosensitive CRC patients were collected to isolate R-CAFs or chemose...

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Detalles Bibliográficos
Autores principales: Shi, Yuanyuan, Zhu, Hua, Jiang, Hang, Yue, Hongqin, Yuan, Fang, Wang, Fusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891287/
https://www.ncbi.nlm.nih.gov/pubmed/36730310
http://dx.doi.org/10.1097/CAD.0000000000001445