A single, improbable B cell receptor mutation confers potent neutralization against cytomegalovirus

Cytomegalovirus (CMV) is a leading cause of infant hearing loss and neurodevelopmental delay, but there are no clinically licensed vaccines to prevent infection, in part due to challenges eliciting neutralizing antibodies. One of the most well-studied targets for CMV vaccines is the viral fusogen gl...

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Detalles Bibliográficos
Autores principales: Jenks, Jennifer A., Amin, Sharmi, Sponholtz, Madeline R., Kumar, Amit, Wrapp, Daniel, Venkatayogi, Sravani, Tu, Joshua J., Karthigeyan, Krithika, Valencia, Sarah M., Connors, Megan, Harnois, Melissa J., Hora, Bhavna, Rochat, Eric, McLellan, Jason S., Wiehe, Kevin, Permar, Sallie R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891502/
https://www.ncbi.nlm.nih.gov/pubmed/36662906
http://dx.doi.org/10.1371/journal.ppat.1011107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891502/
https://www.ncbi.nlm.nih.gov/pubmed/36662906
http://dx.doi.org/10.1371/journal.ppat.1011107

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