Sequencing-based fine-mapping and in silico functional characterization of the 10q24.32 arsenic metabolism efficiency locus across multiple arsenic-exposed populations

Inorganic arsenic is highly toxic and carcinogenic to humans. Exposed individuals vary in their ability to metabolize arsenic, and variability in arsenic metabolism efficiency (AME) is associated with risks of arsenic-related toxicities. Inherited genetic variation in the 10q24.32 region, near the a...

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Detalles Bibliográficos
Autores principales: Chernoff, Meytal Batya, Delgado, Dayana, Tong, Lin, Chen, Lin, Oliva, Meritxell, Tamayo, Lizeth I., Best, Lyle G., Cole, Shelley, Jasmine, Farzana, Kibriya, Muhammad G., Nelson, Heather, Huang, Lei, Haack, Karin, Kent, Jack, Umans, Jason G., Graziano, Joseph, Navas-Acien, Ana, Karagas, Margaret R., Ahsan, Habib, Pierce, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891528/
https://www.ncbi.nlm.nih.gov/pubmed/36668670
http://dx.doi.org/10.1371/journal.pgen.1010588

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891528/
https://www.ncbi.nlm.nih.gov/pubmed/36668670
http://dx.doi.org/10.1371/journal.pgen.1010588

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