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Geometric analysis enables biological insight from complex non-identifiable models using simple surrogates

An enduring challenge in computational biology is to balance data quality and quantity with model complexity. Tools such as identifiability analysis and information criterion have been developed to harmonise this juxtaposition, yet cannot always resolve the mismatch between available data and the gr...

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Detalles Bibliográficos
Autores principales: Browning, Alexander P., Simpson, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891533/
https://www.ncbi.nlm.nih.gov/pubmed/36662831
http://dx.doi.org/10.1371/journal.pcbi.1010844