Tumor-associated nonmyelinating Schwann cell–expressed PVT1 promotes pancreatic cancer kynurenine pathway and tumor immune exclusion

One of the major obstacles to treating pancreatic ductal adenocarcinoma (PDAC) is its immunoresistant microenvironment. The functional importance and molecular mechanisms of Schwann cells in PDAC remains largely elusive. We characterized the gene signature of tumor-associated nonmyelinating Schwann...

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Detalles Bibliográficos
Autores principales: Sun, Chengcao, Ye, Youqiong, Tan, Zhi, Liu, Yuan, Li, Yajuan, Hu, Wei, Liang, Ke, Egranov, Sergey D., Huang, Lisa Angela, Zhang, Zhao, Zhang, Yaohua, Yao, Jun, Nguyen, Tina K., Zhao, Zilong, Wu, Andrew, Marks, Jeffrey R., Caudle, Abigail S., Sahin, Aysegul A., Gao, Jianjun, Gammon, Seth T., Piwnica-Worms, David, Hu, Jian, Chiao, Paul J., Yu, Dihua, Hung, Mien-Chie, Curran, Michael A., Calin, George A., Ying, Haoqiang, Han, Leng, Lin, Chunru, Yang, Liuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891701/
https://www.ncbi.nlm.nih.gov/pubmed/36724291
http://dx.doi.org/10.1126/sciadv.add6995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891701/
https://www.ncbi.nlm.nih.gov/pubmed/36724291
http://dx.doi.org/10.1126/sciadv.add6995

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