Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation

Calcium ion movements between cellular stores and the cytosol govern muscle contraction, the most energy-consuming function in mammals, which confers skeletal myofibers a pivotal role in glycemia regulation. Chronic myoplasmic calcium elevation (“calcium stress”), found in malignant hyperthermia-sus...

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Detalles Bibliográficos
Autores principales: Tammineni, Eshwar R, Figueroa, Lourdes, Manno, Carlo, Varma, Disha, Kraeva, Natalia, Ibarra, Carlos A, Klip, Amira, Riazi, Sheila, Rios, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891728/
https://www.ncbi.nlm.nih.gov/pubmed/36724092
http://dx.doi.org/10.7554/eLife.78874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891728/
https://www.ncbi.nlm.nih.gov/pubmed/36724092
http://dx.doi.org/10.7554/eLife.78874

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