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Reanalysis of ribosome profiling datasets reveals a function of rocaglamide A in perturbing the dynamics of translation elongation via eIF4A
The quickly accumulating ribosome profiling data is an insightful resource for studying the critical details of translation regulation under various biological contexts. Rocaglamide A (RocA), an antitumor heterotricyclic natural compound, has been shown to inhibit translation initiation of a large g...
Autores principales: | Li, Fajin, Fang, Jianhuo, Yu, Yifan, Hao, Sijia, Zou, Qin, Zeng, Qinglin, Yang, Xuerui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891901/ https://www.ncbi.nlm.nih.gov/pubmed/36725859 http://dx.doi.org/10.1038/s41467-023-36290-w |
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