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Insulin-regulated serine and lipid metabolism drive peripheral neuropathy

Diabetes represents a spectrum of disease in which metabolic dysfunction damages multiple organ systems including liver, kidneys and peripheral nerves(1,2). Although the onset and progression of these co-morbidities are linked with insulin resistance, hyperglycaemia and dyslipidaemia(3–7), aberrant...

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Detalles Bibliográficos
Autores principales: Handzlik, Michal K., Gengatharan, Jivani M., Frizzi, Katie E., McGregor, Grace H., Martino, Cameron, Rahman, Gibraan, Gonzalez, Antonio, Moreno, Ana M., Green, Courtney R., Guernsey, Lucie S., Lin, Terry, Tseng, Patrick, Ideguchi, Yoichiro, Fallon, Regis J., Chaix, Amandine, Panda, Satchidananda, Mali, Prashant, Wallace, Martina, Knight, Rob, Gantner, Marin L., Calcutt, Nigel A., Metallo, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891999/
https://www.ncbi.nlm.nih.gov/pubmed/36697822
http://dx.doi.org/10.1038/s41586-022-05637-6