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Insulin-regulated serine and lipid metabolism drive peripheral neuropathy
Diabetes represents a spectrum of disease in which metabolic dysfunction damages multiple organ systems including liver, kidneys and peripheral nerves(1,2). Although the onset and progression of these co-morbidities are linked with insulin resistance, hyperglycaemia and dyslipidaemia(3–7), aberrant...
Autores principales: | Handzlik, Michal K., Gengatharan, Jivani M., Frizzi, Katie E., McGregor, Grace H., Martino, Cameron, Rahman, Gibraan, Gonzalez, Antonio, Moreno, Ana M., Green, Courtney R., Guernsey, Lucie S., Lin, Terry, Tseng, Patrick, Ideguchi, Yoichiro, Fallon, Regis J., Chaix, Amandine, Panda, Satchidananda, Mali, Prashant, Wallace, Martina, Knight, Rob, Gantner, Marin L., Calcutt, Nigel A., Metallo, Christian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9891999/ https://www.ncbi.nlm.nih.gov/pubmed/36697822 http://dx.doi.org/10.1038/s41586-022-05637-6 |
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