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Visualization of translation and protein biogenesis at the ER membrane

The dynamic ribosome–translocon complex, which resides at the endoplasmic reticulum (ER) membrane, produces a major fraction of the human proteome(1,2). It governs the synthesis, translocation, membrane insertion, N-glycosylation, folding and disulfide-bond formation of nascent proteins. Although in...

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Detalles Bibliográficos
Autores principales: Gemmer, Max, Chaillet, Marten L., van Loenhout, Joyce, Cuevas Arenas, Rodrigo, Vismpas, Dimitrios, Gröllers-Mulderij, Mariska, Koh, Fujiet A., Albanese, Pascal, Scheltema, Richard A., Howes, Stuart C., Kotecha, Abhay, Fedry, Juliette, Förster, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892003/
https://www.ncbi.nlm.nih.gov/pubmed/36697828
http://dx.doi.org/10.1038/s41586-022-05638-5