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Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease

The genetics underlying tuberculosis (TB) pathophysiology are poorly understood. Human genome-wide association studies have failed so far to reveal reproducible susceptibility loci, attributed in part to the influence of the underlying Mycobacterium tuberculosis (Mtb) bacterial genotype on the outco...

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Detalles Bibliográficos
Autores principales: Phelan, Jody, Gomez-Gonzalez, Paula Josefina, Andreu, Nuria, Omae, Yosuke, Toyo-Oka, Licht, Yanai, Hideki, Miyahara, Reiko, Nedsuwan, Supalert, de Sessions, Paola Florez, Campino, Susana, Sallah, Neneh, Parkhill, Julian, Smittipat, Nat, Palittapongarnpim, Prasit, Mushiroda, Taisei, Kubo, Michiaki, Tokunaga, Katsushi, Mahasirimongkol, Surakameth, Hibberd, Martin L., Clark, Taane G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892022/
https://www.ncbi.nlm.nih.gov/pubmed/36725857
http://dx.doi.org/10.1038/s41467-023-36282-w