Cargando…

Genome-wide host-pathogen analyses reveal genetic interaction points in tuberculosis disease

The genetics underlying tuberculosis (TB) pathophysiology are poorly understood. Human genome-wide association studies have failed so far to reveal reproducible susceptibility loci, attributed in part to the influence of the underlying Mycobacterium tuberculosis (Mtb) bacterial genotype on the outco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phelan, Jody, Gomez-Gonzalez, Paula Josefina, Andreu, Nuria, Omae, Yosuke, Toyo-Oka, Licht, Yanai, Hideki, Miyahara, Reiko, Nedsuwan, Supalert, de Sessions, Paola Florez, Campino, Susana, Sallah, Neneh, Parkhill, Julian, Smittipat, Nat, Palittapongarnpim, Prasit, Mushiroda, Taisei, Kubo, Michiaki, Tokunaga, Katsushi, Mahasirimongkol, Surakameth, Hibberd, Martin L., Clark, Taane G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892022/ https://www.ncbi.nlm.nih.gov/pubmed/36725857 http://dx.doi.org/10.1038/s41467-023-36282-w

Ejemplares similares

Pathogen lineage-based genome-wide association study identified CD53 as susceptible locus in tuberculosis
por: Omae, Yosuke, et al.
Publicado: (2017)

Evidence for Host-Bacterial Co-evolution via Genome Sequence Analysis of 480 Thai Mycobacterium tuberculosis Lineage 1 Isolates
por: Palittapongarnpim, Prasit, et al.
Publicado: (2018)

Risk for Prison-to-Community Tuberculosis Transmission, Thailand, 2017–2020
por: Miyahara, Reiko, et al.
Publicado: (2023)

A novel Ancestral Beijing sublineage of Mycobacterium tuberculosis suggests the transition site to Modern Beijing sublineages
por: Ajawatanawong, Pravech, et al.
Publicado: (2019)

Identification and in silico functional prediction of lineage-specific SNPs distributed in DosR-related proteins and resuscitation-promoting factor proteins of Mycobacterium tuberculosis
por: Tantivitayakul, Pornpen, et al.
Publicado: (2020)

Homoplastic single nucleotide polymorphisms contributed to phenotypic diversity in Mycobacterium tuberculosis
por: Tantivitayakul, Pornpen, et al.
Publicado: (2020)

Haplotype-specific PCR for NAT2 diplotyping
por: Wichukchinda, Nuanjun, et al.
Publicado: (2020)

Whole-genome single nucleotide variant phylogenetic analysis of Mycobacterium tuberculosis Lineage 1 in endemic regions of Asia and Africa
por: Netikul, Thidarat, et al.
Publicado: (2022)

Revised nomenclature and SNP barcode for Mycobacterium tuberculosis lineage 2
por: Thawornwattana, Yuttapong, et al.
Publicado: (2021)

Identification of ITPA on chromosome 20 as a susceptibility gene for young-onset tuberculosis
por: Nakauchi, Ayaka, et al.
Publicado: (2016)

Contact tracing for tuberculosis, Thailand
por: Imsanguan, Worarat, et al.
Publicado: (2020)

Genomic epidemiology of Streptococcus agalactiae ST283 in Southeast Asia
por: Aiewsakun, Pakorn, et al.
Publicado: (2022)

CYP2E1, GSTM1, and GSTT1 genetic polymorphisms and their associations with susceptibility to antituberculosis drug-induced liver injury in Thai tuberculosis patients
por: Chanhom, Noppadol, et al.
Publicado: (2021)

Distribution of Mycobacterium tuberculosis Lineages and Drug Resistance in Upper Myanmar
por: Phyu, Aye Nyein, et al.
Publicado: (2022)

Molecular characterization of methicillin-resistant Staphylococcus aureus genotype ST764-SCCmec type II in Thailand
por: Kondo, Sumalee, et al.
Publicado: (2022)

Development of a prediction system for anti-tuberculosis drug-induced liver injury in Japanese patients
por: Mushiroda, Taisei, et al.
Publicado: (2016)

COVID-profiler: a webserver for the analysis of SARS-CoV-2 sequencing data
por: Phelan, Jody, et al.
Publicado: (2022)

An integrated in silico immuno-genetic analytical platform provides insights into COVID-19 serological and vaccine targets
por: Ward, Daniel, et al.
Publicado: (2021)

Methylation analysis of Klebsiella pneumoniae from Portuguese hospitals
por: Spadar, Anton, et al.
Publicado: (2021)

SNP-SNP Interactions Discovered by Logic Regression Explain Crohn's Disease Genetics
por: Dinu, Irina, et al.
Publicado: (2012)

Primary macrophages and J774 cells respond differently to infection with Mycobacterium tuberculosis
por: Andreu, Nuria, et al.
Publicado: (2017)

Genomic Sequencing Profiles of Mycobacterium tuberculosis in Mandalay Region, Myanmar
por: Phyu, Aye Nyein, et al.
Publicado: (2023)

An integrated whole genome analysis of Mycobacterium tuberculosis reveals insights into relationship between its genome, transcriptome and methylome
por: Gomez-Gonzalez, Paula J., et al.
Publicado: (2019)

ABCB1 polymorphism is associated with atorvastatin-induced liver injury in Japanese population
por: Fukunaga, Koya, et al.
Publicado: (2016)

Predicting the risk of pulmonary tuberculosis based on the neutrophil-to-lymphocyte ratio at TB screening in HIV-infected individuals
por: Miyahara, Reiko, et al.
Publicado: (2019)

Zika might not be acting alone: Using an ecological study approach to investigate potential co-acting risk factors for an unusual pattern of microcephaly in Brazil
por: Campos, Monica C., et al.
Publicado: (2018)

Robust barcoding and identification of Mycobacterium tuberculosis lineages for epidemiological and clinical studies
por: Napier, Gary, et al.
Publicado: (2020)

Mixed infections in genotypic drug-resistant Mycobacterium tuberculosis
por: Wang, Linfeng, et al.
Publicado: (2023)

Genetics and genomics in Thailand: challenges and opportunities
por: Shotelersuk, Vorasuk, et al.
Publicado: (2014)

Clusters of Drug-Resistant Mycobacterium tuberculosis Detected by Whole-Genome Sequence Analysis of Nationwide Sample, Thailand, 2014–2017
por: Nonghanphithak, Ditthawat, et al.
Publicado: (2021)

Large-scale genomic analysis of Mycobacterium tuberculosis reveals extent of target and compensatory mutations linked to multi-drug resistant tuberculosis
por: Napier, Gary, et al.
Publicado: (2023)

Large-scale reference-free analysis of flavivirus sequences in Aedes aegypti whole genome DNA sequencing data
por: Spadar, Anton, et al.
Publicado: (2023)

Modeling Clostridium difficile in a hospital setting: control and admissions of colonized and symptomatic patients
por: Chamchod, Farida, et al.
Publicado: (2019)

Effects of the proportion of high-risk patients and control strategies on the prevalence of methicillin-resistant Staphylococcus aureus in an intensive care unit
por: Chamchod, Farida, et al.
Publicado: (2019)

Time of highest tuberculosis death risk and associated factors: an observation of 12 years in Northern Thailand
por: Moolphate, Saiyud, et al.
Publicado: (2011)

Personalizing carbamazepine therapy
por: Mushiroda, Taisei, et al.
Publicado: (2011)

CAG-Expansion Haplotype Analysis in a Population with a Low Prevalence of Huntington's Disease
por: Pulkes, Teeratorn, et al.
Publicado: (2014)

Robust detection of point mutations involved in multidrug-resistant Mycobacterium tuberculosis in the presence of co-occurrent resistance markers
por: Libiseller-Egger, Julian, et al.
Publicado: (2020)

Portable sequencing of Mycobacterium tuberculosis for clinical and epidemiological applications
por: Gómez-González, Paula J, et al.
Publicado: (2022)

Functional genetic variation in pe/ppe genes contributes to diversity in Mycobacterium tuberculosis lineages and potential interactions with the human host
por: Gómez-González, Paula Josefina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_m9adehjn3q3da1q1924g8mp0uu