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Synthesis of new diphenyl urea-clubbed imine analogs and its Implications in diabetic management through in vitro and in silico approaches

Type II diabetes mellitus (T2DM) is a global health issue with high rate of prevalence. The inhibition of α-glucosidase enzyme has prime importance in the management of T2DM. This study was established to synthesize Schiff bases of 1,3-dipheny urea (3a–y) and to investigate their in vitro anti-diabe...

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Detalles Bibliográficos
Autores principales: Pasha, Anam Rubbab, Khan, Ajmal, Ullah, Saeed, Halim, Sobia Ahsan, Hussain, Javid, Khalid, Muhammad, Naseer, Muhammad Moazzam, El-kott, Attalla F., Negm, Sally, Al-Harrasi, Ahmed, Shafiq, Zahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892044/
https://www.ncbi.nlm.nih.gov/pubmed/36725861
http://dx.doi.org/10.1038/s41598-023-28828-1