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Ginkgolic acid promotes inflammation and macrophage apoptosis via SUMOylation and NF-κB pathways in sepsis

BACKGROUND: Excessive inflammation and increased apoptosis of macrophages contribute to organ damage and poor prognosis of sepsis. Ginkgolic acid (GA) is a natural constituent extracted from the leaves of Ginkgo biloba, that can regulate inflammation and apoptosis. The present study aims to investig...

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Detalles Bibliográficos
Autores principales: Liu, Xinyong, Chen, Longwang, Zhang, Chen, Dong, Wei, Liu, Hongbing, Xiao, Zhong, Wang, Kang, Zhang, Yaolu, Tang, Yahui, Hong, Guangliang, Lu, Zhongqiu, Zhao, Guangju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892062/
https://www.ncbi.nlm.nih.gov/pubmed/36743669
http://dx.doi.org/10.3389/fmed.2022.1108882