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Transferrin-modified chitosan nanoparticles for targeted nose-to-brain delivery of proteins

Nose-to-brain delivery presents a promising alternative route compared to classical blood–brain barrier passage, especially for the delivery of high molecular weight drugs. In general, macromolecules are rapidly degraded in physiological environment. Therefore, nanoparticulate systems can be used to...

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Detalles Bibliográficos
Autores principales: Gabold, Bettina, Adams, Friederike, Brameyer, Sophie, Jung, Kirsten, Ried, Christian L., Merdan, Thomas, Merkel, Olivia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892103/
https://www.ncbi.nlm.nih.gov/pubmed/36207657
http://dx.doi.org/10.1007/s13346-022-01245-z