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Transferrin-modified chitosan nanoparticles for targeted nose-to-brain delivery of proteins
Nose-to-brain delivery presents a promising alternative route compared to classical blood–brain barrier passage, especially for the delivery of high molecular weight drugs. In general, macromolecules are rapidly degraded in physiological environment. Therefore, nanoparticulate systems can be used to...
Autores principales: | Gabold, Bettina, Adams, Friederike, Brameyer, Sophie, Jung, Kirsten, Ried, Christian L., Merdan, Thomas, Merkel, Olivia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892103/ https://www.ncbi.nlm.nih.gov/pubmed/36207657 http://dx.doi.org/10.1007/s13346-022-01245-z |
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