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Toll-like receptor-3 contributes to the development of aortic valve stenosis

Aortic valve stenosis (AS) development is driven by distinct molecular and cellular mechanisms which include inflammatory pathways. Toll-like-receptor-3 (TLR3) is a lysosomal pattern-recognition receptor that binds double-stranded RNA and promotes pro-inflammatory cellular responses. In recent years...

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Detalles Bibliográficos
Autores principales: Niepmann, Sven Thomas, Willemsen, Nicola, Boucher, Ann Sophie, Stei, Marta, Goody, Philip, Zietzer, Andreas, Bulic, Marko, Billig, Hannah, Odainic, Alexandru, Weisheit, Christina Katharina, Quast, Christine, Adam, Matti, Schmidt, Susanne V., Bakhtiary, Farhad, Jansen, Felix, Nickenig, Georg, Latz, Eike, Zimmer, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892139/
https://www.ncbi.nlm.nih.gov/pubmed/36723728
http://dx.doi.org/10.1007/s00395-023-00980-9