Gene expression profiling in NOD mice reveals that B cells are highly educated by the pancreatic environment during autoimmune diabetes

AIMS/HYPOTHESIS: B cells play an important role in driving the development of type 1 diabetes; however, it remains unclear how they contribute to local beta cell destruction during disease progression. Here, we use gene expression profiling of B cell subsets identified in inflamed pancreatic tissue...

Descripción completa

Detalles Bibliográficos
Autores principales: Boldison, Joanne, Hopkinson, Jessica R., Davies, Joanne, Pearson, James A., Leete, Pia, Richardson, Sarah, Morgan, Noel G., Wong, F. Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892163/
https://www.ncbi.nlm.nih.gov/pubmed/36508037
http://dx.doi.org/10.1007/s00125-022-05839-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892163/
https://www.ncbi.nlm.nih.gov/pubmed/36508037
http://dx.doi.org/10.1007/s00125-022-05839-7

Ejemplares similares