Cargando…
Gene expression profiling in NOD mice reveals that B cells are highly educated by the pancreatic environment during autoimmune diabetes
AIMS/HYPOTHESIS: B cells play an important role in driving the development of type 1 diabetes; however, it remains unclear how they contribute to local beta cell destruction during disease progression. Here, we use gene expression profiling of B cell subsets identified in inflamed pancreatic tissue...
Autores principales: | Boldison, Joanne, Hopkinson, Jessica R., Davies, Joanne, Pearson, James A., Leete, Pia, Richardson, Sarah, Morgan, Noel G., Wong, F. Susan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892163/ https://www.ncbi.nlm.nih.gov/pubmed/36508037 http://dx.doi.org/10.1007/s00125-022-05839-7 |
Ejemplares similares
-
Phenotypically distinct anti-insulin B cells repopulate pancreatic islets after anti-CD20 treatment in NOD mice
por: Boldison, Joanne, et al.
Publicado: (2019) -
B cell depletion reduces T cell activation in pancreatic islets in a murine autoimmune diabetes model
por: Da Rosa, Larissa C., et al.
Publicado: (2018) -
Regulatory B Cells: Role in Type 1 Diabetes
por: Boldison, Joanne, et al.
Publicado: (2021) -
Footprints of Immune Cells in the Pancreas in Type 1 Diabetes; to “B” or Not to “B”: Is That Still the Question?
por: Leete, Pia, et al.
Publicado: (2021) -
NOD mice, susceptible to pancreatic autoimmunity, demonstrate delayed growth of pancreatic cancer
por: Dooley, James, et al.
Publicado: (2017)