Identification of Isonitrile‐Containing Natural Products in Complex Biological Matrices through Ligation with Chlorooximes

Isonitrile‐containing natural products have garnered attention for their manifold bioactivities but are difficult to detect and isolate due to the chemical lability of the isonitrile functional group. Here, we used the isonitrile‐chlorooxime ligation (INC) in a reactivity‐based screening (RBS) proto...

Descripción completa

Detalles Bibliográficos
Autores principales: Schäfer, Rebecca J. B., Wilson, Kayla, Biedermann, Maurice, Moore, Bradley S., Sieber, Simon, Wennemers, Helma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892309/
https://www.ncbi.nlm.nih.gov/pubmed/36331430
http://dx.doi.org/10.1002/chem.202203277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892309/
https://www.ncbi.nlm.nih.gov/pubmed/36331430
http://dx.doi.org/10.1002/chem.202203277

Ejemplares similares