Quantitative omics analyses of NCOA4 deficiency reveal an integral role of ferritinophagy in iron homeostasis of hippocampal neuronal HT22 cells

INTRODUCTION: Neurons require iron to support their metabolism, growth, and differentiation, but are also susceptible to iron-induced oxidative stress and cytotoxicity. Ferritin, a cytosolic iron storage unit, mediates cellular adaptation to fluctuations in iron delivery. NCOA4 has been characterize...

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Detalles Bibliográficos
Autores principales: Bengson, Emily F., Guggisberg, Cole A., Bastian, Thomas W., Georgieff, Michael K., Ryu, Moon-Suhn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892431/
https://www.ncbi.nlm.nih.gov/pubmed/36742433
http://dx.doi.org/10.3389/fnut.2023.1054852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892431/
https://www.ncbi.nlm.nih.gov/pubmed/36742433
http://dx.doi.org/10.3389/fnut.2023.1054852

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