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Quantitative omics analyses of NCOA4 deficiency reveal an integral role of ferritinophagy in iron homeostasis of hippocampal neuronal HT22 cells

INTRODUCTION: Neurons require iron to support their metabolism, growth, and differentiation, but are also susceptible to iron-induced oxidative stress and cytotoxicity. Ferritin, a cytosolic iron storage unit, mediates cellular adaptation to fluctuations in iron delivery. NCOA4 has been characterize...

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Detalles Bibliográficos
Autores principales:	Bengson, Emily F., Guggisberg, Cole A., Bastian, Thomas W., Georgieff, Michael K., Ryu, Moon-Suhn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Nutrition
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892431/ https://www.ncbi.nlm.nih.gov/pubmed/36742433 http://dx.doi.org/10.3389/fnut.2023.1054852

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