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Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation

IL-27 is an IL-12 family cytokine with immune regulatory properties, capable of modulating inflammatory responses, including autoimmunity. While extensive studies investigated the major target cells of IL-27 mediating its functions, the source of IL-27 especially during tissue specific autoimmune in...

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Detalles Bibliográficos
Autores principales: Kim, Dongkyun, Kim, Sohee, Kang, Myung-su, Yin, Zhinan, Min, Booki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892501/
https://www.ncbi.nlm.nih.gov/pubmed/36725904
http://dx.doi.org/10.1038/s41598-023-27413-w