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HuMSC-EV induce monocyte/macrophage mobilization to orchestrate neovascularization in wound healing process following radiation injury

This study aims to investigate the mechanisms of human mesenchymal stem cell-derived extracellular vesicles (HuMSC-EV)-induced proangiogenic paracrine effects after radiation injury. HuMSC-EV were locally administered in mice hindlimb following 80-Gy X-ray irradiation and animals were monitored at d...

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Detalles Bibliográficos
Autores principales: Loinard, Céline, Ribault, Alexandre, Lhomme, Bruno, Benderitter, Marc, Flamant, Stéphane, Paul, Sandrine, Dubois, Valérie, Lai, Ruenn Chai, Lim, Sai Kiang, Tamarat, Radia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892506/
https://www.ncbi.nlm.nih.gov/pubmed/36725841
http://dx.doi.org/10.1038/s41420-023-01335-y