Cargando…

LncRNA TINCR impairs the efficacy of immunotherapy against breast cancer by recruiting DNMT1 and downregulating MiR-199a-5p via the STAT1–TINCR-USP20-PD-L1 axis

Although programmed death-ligand 1 (PD-L1) inhibitors have achieved some therapeutic success in breast cancer, their efficacy is limited by low therapeutic response rates, which is closely related to the immune escape of breast cancer cells. Tissue differentiation inducing non-protein coding RNA (TI...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qin, Li, Guozheng, Ma, Xin, Liu, Lei, Liu, Jiena, Yin, Yanling, Li, Hui, Chen, Yihai, Zhang, Xin, Zhang, Lei, Sun, Liyang, Ai, Jing, Xu, Shouping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892521/
https://www.ncbi.nlm.nih.gov/pubmed/36725842
http://dx.doi.org/10.1038/s41419-023-05609-2