Cargando…
LncRNA TINCR impairs the efficacy of immunotherapy against breast cancer by recruiting DNMT1 and downregulating MiR-199a-5p via the STAT1–TINCR-USP20-PD-L1 axis
Although programmed death-ligand 1 (PD-L1) inhibitors have achieved some therapeutic success in breast cancer, their efficacy is limited by low therapeutic response rates, which is closely related to the immune escape of breast cancer cells. Tissue differentiation inducing non-protein coding RNA (TI...
Autores principales: | Wang, Qin, Li, Guozheng, Ma, Xin, Liu, Lei, Liu, Jiena, Yin, Yanling, Li, Hui, Chen, Yihai, Zhang, Xin, Zhang, Lei, Sun, Liyang, Ai, Jing, Xu, Shouping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892521/ https://www.ncbi.nlm.nih.gov/pubmed/36725842 http://dx.doi.org/10.1038/s41419-023-05609-2 |
Ejemplares similares
-
LncRNA TINCR favors tumorigenesis via STAT3–TINCR–EGFR-feedback loop by recruiting DNMT1 and acting as a competing endogenous RNA in human breast cancer
por: Wang, Qin, et al.
Publicado: (2021) -
METTL14 suppresses pyroptosis and diabetic cardiomyopathy by downregulating TINCR lncRNA
por: Meng, Liping, et al.
Publicado: (2022) -
TINCR: An lncRNA with dual functions in the carcinogenesis process
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2020) -
lncRNA TINCR knockdown inhibits colon cancer cells via regulation of autophagy
por: Xu, Jianhua, et al.
Publicado: (2023) -
LncRNA TINCR attenuates cardiac hypertrophy by epigenetically silencing CaMKII
por: Shao, Mingjing, et al.
Publicado: (2017)