Endoplasmic reticulum stress inhibition ameliorated WFS1 expression alterations and reduced pancreatic islets’ insulin secretion induced by high-fat diet in rats

Endoplasmic reticulum (ER) stress is involved in the development of glucose homeostasis impairment. When ER stress occurs, the unfolded protein response (UPR) is activated to cope with it. One of the UPR components is WFS1 (Wolfram syndrome 1), which plays important roles in ER homeostasis and pancr...

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Detalles Bibliográficos
Autores principales: Binayi, Fateme, Fahanik-Babaei, Javad, Salimi, Mina, Eskandari, Farzaneh, Sahraei, Mohammad, Ghorbani Ranjbary, Ali, Ghasemi, Rasoul, Hedayati, Mehdi, Khodagholi, Fariba, Eliassi, Afsaneh, Zardooz, Homeira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892558/
https://www.ncbi.nlm.nih.gov/pubmed/36725880
http://dx.doi.org/10.1038/s41598-023-28329-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892558/
https://www.ncbi.nlm.nih.gov/pubmed/36725880
http://dx.doi.org/10.1038/s41598-023-28329-1

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