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Endoplasmic reticulum stress inhibition ameliorated WFS1 expression alterations and reduced pancreatic islets’ insulin secretion induced by high-fat diet in rats
Endoplasmic reticulum (ER) stress is involved in the development of glucose homeostasis impairment. When ER stress occurs, the unfolded protein response (UPR) is activated to cope with it. One of the UPR components is WFS1 (Wolfram syndrome 1), which plays important roles in ER homeostasis and pancr...
Autores principales: | Binayi, Fateme, Fahanik-Babaei, Javad, Salimi, Mina, Eskandari, Farzaneh, Sahraei, Mohammad, Ghorbani Ranjbary, Ali, Ghasemi, Rasoul, Hedayati, Mehdi, Khodagholi, Fariba, Eliassi, Afsaneh, Zardooz, Homeira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892558/ https://www.ncbi.nlm.nih.gov/pubmed/36725880 http://dx.doi.org/10.1038/s41598-023-28329-1 |
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