HIF-PHD inhibitor regulates the function of group2 innate lymphoid cells and polarization of M2 macrophages

Hypoxia-inducible factor-prolyl hydroxylase (HIF-PHD) inhibitors are therapeutic agents for renal anemia that work through HIF2-mediated upregulation of erythropoietin (EPO) and have also been reported to suppress renal fibrosis. Group 2 innate lymphoid cells (ILC2s) have been proven to be involved...

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Detalles Bibliográficos
Autores principales: Nagashima, Ryuichi, Ishikawa, Hiroki, Kuno, Yoshihiro, Kohda, Chikara, Iyoda, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892566/
https://www.ncbi.nlm.nih.gov/pubmed/36725898
http://dx.doi.org/10.1038/s41598-023-29161-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892566/
https://www.ncbi.nlm.nih.gov/pubmed/36725898
http://dx.doi.org/10.1038/s41598-023-29161-3

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