Investigation on acquired palbociclib resistance by LC-MS based multi-omics analysis

Palbociclib is a specific CDK4/6 inhibitor that has been widely applied in multiple types of tumors. Different from cytotoxic drugs, the anticancer mechanism of palbociclib mainly depends on cell cycle inhibition. Therefore, the resistance mechanism is different. For clinical cancer patients, drug r...

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Detalles Bibliográficos
Autores principales: Xue, Zhichao, Zeng, Jiaming, Yin, Xinchi, Li, Yongshu, Meng, Bo, Zhao, Yang, Fang, Xiang, Gong, Xiaoyun, Dai, Xinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892630/
https://www.ncbi.nlm.nih.gov/pubmed/36743215
http://dx.doi.org/10.3389/fmolb.2023.1116398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892630/
https://www.ncbi.nlm.nih.gov/pubmed/36743215
http://dx.doi.org/10.3389/fmolb.2023.1116398

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