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Investigation on acquired palbociclib resistance by LC-MS based multi-omics analysis
Palbociclib is a specific CDK4/6 inhibitor that has been widely applied in multiple types of tumors. Different from cytotoxic drugs, the anticancer mechanism of palbociclib mainly depends on cell cycle inhibition. Therefore, the resistance mechanism is different. For clinical cancer patients, drug r...
Autores principales: | Xue, Zhichao, Zeng, Jiaming, Yin, Xinchi, Li, Yongshu, Meng, Bo, Zhao, Yang, Fang, Xiang, Gong, Xiaoyun, Dai, Xinhua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892630/ https://www.ncbi.nlm.nih.gov/pubmed/36743215 http://dx.doi.org/10.3389/fmolb.2023.1116398 |
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