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CpH methylome analysis in human cortical neurons identifies novel gene pathways and drug targets for opioid use disorder
INTRODUCTION: DNA methylation (DNAm), an epigenetic mechanism, has been associated with opioid use disorder (OUD) in preclinical and human studies. However, most of the studies have focused on DNAm at CpG sites. DNAm at non-CpG sites (mCpHs, where H indicates A, T, or C) has been recently shown to h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892724/ https://www.ncbi.nlm.nih.gov/pubmed/36745154 http://dx.doi.org/10.3389/fpsyt.2022.1078894 |