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Frequency, underdiagnosis, and heterogeneity of epidermal growth factor receptor exon 20 insertion mutations using real‐world genomic datasets

Epidermal growth factor receptor (EGFR) exon 20 insertion mutations (ex20ins) account for ≤ 12% of all EGFR‐mutant nonsmall cell lung cancers. We analysed real‐world datasets to determine the frequency of ex20ins variants, and the ability of polymerase chain reaction (PCR) and next‐generation sequen...

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Detalles Bibliográficos
Autores principales: Viteri, Santiago, Minchom, Anna, Bazhenova, Lyudmila, Ou, Sai‐Hong Ignatius, Bauml, Joshua M., Shell, Scott A., Schaffer, Michael, Gu, Junchen, Rose, Jennifer B., Curtin, Joshua C., Mahadevia, Parthiv, Girard, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892822/
https://www.ncbi.nlm.nih.gov/pubmed/36269676
http://dx.doi.org/10.1002/1878-0261.13327