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ALKBH1‐mediated m(1)A demethylation of METTL3 mRNA promotes the metastasis of colorectal cancer by downregulating SMAD7 expression

Colorectal cancer (CRC) is one of the most common malignancies, and the main cause of death from CRC is tumor metastasis. m(1)A RNA modification plays critical role in many biological processes. However, the role of m(1)A modification in CRC remains unclear. Here, we find that the m(1)A demethylase...

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Detalles Bibliográficos
Autores principales: Chen, Wenwen, Wang, Hao, Mi, Shuyi, Shao, Liming, Xu, Zhipeng, Xue, Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9892827/
https://www.ncbi.nlm.nih.gov/pubmed/36550779
http://dx.doi.org/10.1002/1878-0261.13366