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Phenotypic screen identifies the natural product silymarin as a novel anti-inflammatory analgesic

Sensory neuron hyperexcitability is a critical driver of pathological pain and can result from axon damage, inflammation, or neuronal stress. G-protein coupled receptor signaling can induce pain amplification by modulating the activation of Trp-family ionotropic receptors and voltage-gated ion chann...

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Detalles Bibliográficos
Autores principales: DuBreuil, Daniel M, Lai, Xiaofan, Zhu, Kevin, Chahyadinata, Gracesenia, Perner, Caroline, Chiang, Brenda M, Battenberg, Ashley, Sokol, Caroline L, Wainger, Brian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893088/
https://www.ncbi.nlm.nih.gov/pubmed/36526437
http://dx.doi.org/10.1177/17448069221148351