Cargando…
Phenotypic screen identifies the natural product silymarin as a novel anti-inflammatory analgesic
Sensory neuron hyperexcitability is a critical driver of pathological pain and can result from axon damage, inflammation, or neuronal stress. G-protein coupled receptor signaling can induce pain amplification by modulating the activation of Trp-family ionotropic receptors and voltage-gated ion chann...
Autores principales: | DuBreuil, Daniel M, Lai, Xiaofan, Zhu, Kevin, Chahyadinata, Gracesenia, Perner, Caroline, Chiang, Brenda M, Battenberg, Ashley, Sokol, Caroline L, Wainger, Brian J |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893088/ https://www.ncbi.nlm.nih.gov/pubmed/36526437 http://dx.doi.org/10.1177/17448069221148351 |
Ejemplares similares
-
A high-content platform for physiological profiling and unbiased classification of individual neurons
por: DuBreuil, Daniel M., et al.
Publicado: (2021) -
Protocol for dissection and culture of murine dorsal root ganglia neurons to study neuropeptide release
por: Perner, Caroline, et al.
Publicado: (2021) -
Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated Ca(V)2.2 Calcium Channel Activity in Peripheral Axon Terminals Innervating Skin
por: DuBreuil, Daniel M., et al.
Publicado: (2021) -
Pharmacological Profiling of Purified Human Stem Cell-Derived and Primary Mouse Motor Neurons
por: Moakley, Daniel, et al.
Publicado: (2019) -
Silymarin as a Natural Antioxidant: An Overview of the Current Evidence and Perspectives
por: Surai, Peter F.
Publicado: (2015)