Memantine as a neuroprotective agent in ischemic stroke: Preclinical and clinical analysis

The primary mechanism for neuron death after an ischemic stroke is excitotoxic injury. Excessive depolarization leads to NMDA-mediated calcium entry to the neuron and, subsequently, cellular death. Therefore, the inhibition of the NMDA channel has been proposed as a neuroprotective measure in ischem...

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Detalles Bibliográficos
Autores principales: Pichardo-Rojas, Diego, Pichardo-Rojas, Pavel Salvador, Cornejo-Bravo, José Manuel, Serrano-Medina, Aracely
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893121/
https://www.ncbi.nlm.nih.gov/pubmed/36743806
http://dx.doi.org/10.3389/fnins.2023.1096372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893121/
https://www.ncbi.nlm.nih.gov/pubmed/36743806
http://dx.doi.org/10.3389/fnins.2023.1096372

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