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Macrophage-derived GPNMB trapped by fibrotic extracellular matrix promotes pulmonary fibrosis

Pulmonary fibrosis (PF) is a form of progressive lung disease characterized by chronic inflammation and excessive extracellular matrix (ECM) deposition. However, the protein changes in fibrotic ECM during PF and their contribution to fibrosis progression are unclear. Here we show that changes in exp...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Zhang, Xinxin, Long, Min, Yuan, Mengqin, Yin, Juan, Luo, Wei, Wang, Sha, Cai, Yu, Jiang, Wei, Chao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893197/
https://www.ncbi.nlm.nih.gov/pubmed/36732560
http://dx.doi.org/10.1038/s42003-022-04333-5