Identification of Hetero-aggregates in Antibody Co-formulations by Multi-dimensional Liquid Chromatography Coupled to Mass Spectrometry

[Image: see text] Antibody combination therapies have become viable therapeutic treatment options for certain severe diseases such as cancer. The co-formulation production approach is intrinsically associated with more complex drug product variant profiles and creates more challenges for analytical...

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Detalles Bibliográficos
Autores principales: Kuhne, Felix, Heinrich, Katrin, Winter, Martin, Fichtl, Jürgen, Hoffmann, Gabriel, Zähringer, Franziska, Spitzauer, Katharina, Meier, Monika, Khan, Tarik A., Bonnington, Lea, Wagner, Katharina, Stracke, Jan Olaf, Reusch, Dietmar, Wegele, Harald, Mormann, Michael, Bulau, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893218/
https://www.ncbi.nlm.nih.gov/pubmed/36669833
http://dx.doi.org/10.1021/acs.analchem.2c03099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893218/
https://www.ncbi.nlm.nih.gov/pubmed/36669833
http://dx.doi.org/10.1021/acs.analchem.2c03099

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