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Comparing therapeutic modulators of the SOD1 G93A Amyotrophic Lateral Sclerosis mouse pathophysiology

INTRODUCTION: Amyotrophic Lateral Sclerosis (ALS) is a paralyzing, multifactorial neurodegenerative disease with limited therapeutics and no known cure. The study goal was to determine which pathophysiological treatment targets appear most beneficial. METHODS: A big data approach was used to analyze...

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Detalles Bibliográficos
Autores principales: Lee, Albert J. B., Kittel, Tyler E., Kim, Renaid B., Bach, Thao-Nguyen, Zhang, Tian, Mitchell, Cassie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893287/
https://www.ncbi.nlm.nih.gov/pubmed/36741054
http://dx.doi.org/10.3389/fnins.2022.1111763