Clinical significance of neoadjuvant chemotherapy for locally advanced colorectal cancer patients with deficient mismatch repair: possibly residual value in the era of immunotherapy

BACKGROUND: Deficient mismatch repair (dMMR) or microsatellite instability is one of the well-established molecular biomarkers in colorectal cancer (CRC). The efficiency of neoadjuvant chemotherapy (NAC) in locally advanced colorectal cancer (LACC) patients with dMMR is unclear. OBJECTIVES: We asses...

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Detalles Bibliográficos
Autores principales: Chen, Mian, Chen, Junguo, Huang, Jun, Liu, Huashan, Cao, Wuteng, Luo, Shuangling, Liu, Zhanzhen, Hu, Huanxin, Lai, Sicong, Hou, Yujie, Kang, Liang, Huang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893354/
https://www.ncbi.nlm.nih.gov/pubmed/36742014
http://dx.doi.org/10.1177/17562848221150306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893354/
https://www.ncbi.nlm.nih.gov/pubmed/36742014
http://dx.doi.org/10.1177/17562848221150306

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