Cyclohexane-1,3-dione Derivatives as Future Therapeutic Agents for NSCLC: QSAR Modeling, In Silico ADME-Tox Properties, and Structure-Based Drug Designing Approach

[Image: see text] The abnormal expression of the c-Met tyrosine kinase has been linked to the proliferation of several human cancer cell lines, including non-small-cell lung cancer (NSCLC). In this context, the identification of new c-Met inhibitors based on heterocyclic small molecules could pave t...

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Detalles Bibliográficos
Autores principales: Daoui, Ossama, Elkhattabi, Souad, Bakhouch, Mohamed, Belaidi, Salah, Bhandare, Richie R., Shaik, Afzal B., Mali, Suraj N., Chtita, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893467/
https://www.ncbi.nlm.nih.gov/pubmed/36743017
http://dx.doi.org/10.1021/acsomega.2c07585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893467/
https://www.ncbi.nlm.nih.gov/pubmed/36743017
http://dx.doi.org/10.1021/acsomega.2c07585

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