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Oligodendrogenesis and myelination tracing in a CRISPR/Cas9-engineered brain microphysiological system

INTRODUCTION: Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system (CNS). Although OLs can be differentiated from human-induced pluripotent stem cells (hiPSCs), the in vitro modeling of axon myelination in human cells remains challenging. Brain microphysiological systems...

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Detalles Bibliográficos
Autores principales: Romero, July Carolina, Berlinicke, Cynthia, Chow, Sharon, Duan, Yukan, Wang, Yifei, Chamling, Xitiz, Smirnova, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893511/
https://www.ncbi.nlm.nih.gov/pubmed/36744062
http://dx.doi.org/10.3389/fncel.2022.1094291