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Oligodendrogenesis and myelination tracing in a CRISPR/Cas9-engineered brain microphysiological system
INTRODUCTION: Oligodendrocytes (OLs) are the myelin-forming cells of the central nervous system (CNS). Although OLs can be differentiated from human-induced pluripotent stem cells (hiPSCs), the in vitro modeling of axon myelination in human cells remains challenging. Brain microphysiological systems...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893511/ https://www.ncbi.nlm.nih.gov/pubmed/36744062 http://dx.doi.org/10.3389/fncel.2022.1094291 |