Alpha‐kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway

BACKGROUND: Alpha‐kinase 1 (ALPK1) is a master regulator in inflammation and has been proved to promote renal fibrosis by promoting the production of IL-1β in diabetic nephropathy (DN) mice. Pyroptosis is involved in high glucose (HG)-induced tubular cells injury, characterized by activation of Gasd...

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Detalles Bibliográficos
Autores principales: Cui, Xinyuan, Li, Yifu, Yuan, Shuguang, Huang, Yao, Chen, Xiaojun, Han, Yachun, Liu, Zhiwen, Li, Zheng, Xiao, Yang, Wang, Youliang, Sun, Lin, Liu, Hong, Zhu, Xuejing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893546/
https://www.ncbi.nlm.nih.gov/pubmed/36732854
http://dx.doi.org/10.1186/s40659-023-00416-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893546/
https://www.ncbi.nlm.nih.gov/pubmed/36732854
http://dx.doi.org/10.1186/s40659-023-00416-7

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