Cargando…

Alpha‐kinase1 promotes tubular injury and interstitial inflammation in diabetic nephropathy by canonical pyroptosis pathway

BACKGROUND: Alpha‐kinase 1 (ALPK1) is a master regulator in inflammation and has been proved to promote renal fibrosis by promoting the production of IL-1β in diabetic nephropathy (DN) mice. Pyroptosis is involved in high glucose (HG)-induced tubular cells injury, characterized by activation of Gasd...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Xinyuan, Li, Yifu, Yuan, Shuguang, Huang, Yao, Chen, Xiaojun, Han, Yachun, Liu, Zhiwen, Li, Zheng, Xiao, Yang, Wang, Youliang, Sun, Lin, Liu, Hong, Zhu, Xuejing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893546/ https://www.ncbi.nlm.nih.gov/pubmed/36732854 http://dx.doi.org/10.1186/s40659-023-00416-7

Ejemplares similares

TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease
por: Wang, Youliang, et al.
Publicado: (2019)

p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy
por: Xu, Xiaoxuan, et al.
Publicado: (2016)

Tubular atrophy/interstitial fibrosis scores of Oxford classification combinded with proteinuria level at biopsy provides earlier risk prediction in lgA nephropathy
por: Zhu, Xuejing, et al.
Publicado: (2017)

Author Correction: p66Shc: A novel biomarker of tubular oxidative injury in patients with diabetic nephropathy
por: Xu, Xiaoxuan, et al.
Publicado: (2020)

DsbA-L interacting with catalase in peroxisome improves tubular oxidative damage in diabetic nephropathy
por: Liu, Yan, et al.
Publicado: (2023)

Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis
por: Han, Yachun, et al.
Publicado: (2018)

Uromodulin deficiency alters tubular injury and interstitial inflammation but not fibrosis in experimental obstructive nephropathy
por: Maydan, Olena, et al.
Publicado: (2018)

Serum homocysteine is associated with tubular interstitial lesions at the early stage of IgA nephropathy
por: Li, Zizhen, et al.
Publicado: (2022)

Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy
por: Han, Yachun, et al.
Publicado: (2021)

The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy
por: Zhao, Weichen, et al.
Publicado: (2022)

Nicotinamide reduces renal interstitial fibrosis by suppressing tubular injury and inflammation
por: Zheng, Meiling, et al.
Publicado: (2019)

Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy
por: Xiao, Li, et al.
Publicado: (2014)

Plasma uric acid level indicates tubular interstitial leisions at early stage of IgA nephropathy
por: Zhou, Jingjing, et al.
Publicado: (2014)

Spleen Tyrosine Kinase Inhibition Ameliorates Tubular Inflammation in IgA Nephropathy
por: Yiu, Wai Han, et al.
Publicado: (2021)

Recent advances in renal interstitial fibrosis and tubular atrophy after kidney transplantation
por: Li, Xiaojun, et al.
Publicado: (2014)

AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress
por: Xiong, Shan, et al.
Publicado: (2020)

DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity
por: Yang, Ming, et al.
Publicado: (2019)

NLRP3-mediated pyroptosis in diabetic nephropathy
por: Wan, Jiayi, et al.
Publicado: (2022)

Predictive value of sub classification of focal segmental glomerular sclerosis in Oxford classification of IgA nephropathy
por: Yu, Fang, et al.
Publicado: (2021)

GSDME-dependent pyroptosis signaling pathway in diabetic nephropathy
por: Li, Shengyu, et al.
Publicado: (2023)

Shear wave elastography findings in Immunoglobulin A Nephropathy patients: is it more specific and sensitive for interstitial fibrosis or interstitial fibrosis/tubular atrophy?
por: Turgutalp, Kenan, et al.
Publicado: (2020)

Treatment of Membranous Nephropathy by Disulfiram through Inhibition of Podocyte Pyroptosis
por: Lv, Daoyuan, et al.
Publicado: (2022)

Hepatocytes Are Resistant to Cell Death From Canonical and Non-Canonical Inflammasome-Activated Pyroptosis
por: Sun, Ping, et al.
Publicado: (2021)

Induction of Pyroptosis in Renal Tubular Epithelial Cells Using High Glucose
por: Liu, Yinghong, et al.
Publicado: (2022)

HIF‐1α ameliorates tubular injury in diabetic nephropathy via HO‐1–mediated control of mitochondrial dynamics
por: Jiang, Na, et al.
Publicado: (2020)

Identification of pyroptosis-related genes and potential drugs in diabetic nephropathy
por: Yan, Meng, et al.
Publicado: (2023)

Interstitial inflammation and interstitial fibrosis and tubular atrophy predict renal survival in lupus nephritis
por: Wilson, Parker C, et al.
Publicado: (2018)

Mini-Review: GSDME-Mediated Pyroptosis in Diabetic Nephropathy
por: Li, Wen, et al.
Publicado: (2021)

Complement induces podocyte pyroptosis in membranous nephropathy by mediating mitochondrial dysfunction
por: Wang, Hui, et al.
Publicado: (2022)

Norcantharidin Inhibits Renal Interstitial Fibrosis by Blocking the Tubular Epithelial-Mesenchymal Transition
por: Li, Ying, et al.
Publicado: (2013)

The Role of TLR4 on PGC-1α-Mediated Oxidative Stress in Tubular Cell in Diabetic Kidney Disease
por: Yuan, Shuguang, et al.
Publicado: (2018)

DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury
por: Xiong, Jiachuan, et al.
Publicado: (2022)

Overexpression of aquaporin 2 in renal tubular epithelial cells alleviates pyroptosis
por: Fan, Yu, et al.
Publicado: (2021)

Primary Sjögren syndrome-associated acute interstitial nephritis and type 3 renal tubular acidosis in a patient with thin basement membrane nephropathy: A case report
por: Du, Tian, et al.
Publicado: (2020)

GSDMD-mediated pyroptosis: a critical mechanism of diabetic nephropathy
por: Zuo, Yi, et al.
Publicado: (2021)

Correction: Norcantharidin Inhibits Renal Interstitial Fibrosis by Blocking the Tubular Epithelial-Mesenchymal Transition
por: Li, Ying, et al.
Publicado: (2013)

Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy
por: Li, ChangYan, et al.
Publicado: (2022)

The Rho kinase signaling pathway participates in tubular mitochondrial oxidative injury and apoptosis in uric acid nephropathy
por: Su, Yan, et al.
Publicado: (2021)

Ablation of GSDMD Improves Outcome of Ischemic Stroke Through Blocking Canonical and Non-canonical Inflammasomes Dependent Pyroptosis in Microglia
por: Wang, Kankai, et al.
Publicado: (2020)

A high value of fibrinogen in immunoglobulin A nephropathy patients is associated with a worse renal tubular atrophy/interstitial fibrosis score
por: Tu, Mengyun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ksq2qde3htthttobnktch0759i