Cargando…

PMCA inhibition reverses drug resistance in clinically refractory cancer patient-derived models

BACKGROUND: Cancer cells have developed molecular strategies to cope with evolutionary stressors in the dynamic tumor microenvironment. Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC1α) is a metabolic rheostat that regulates diverse cellular adaptive behaviors, including growth and...

Descripción completa

Detalles Bibliográficos
Autores principales: Park, Ki Cheong, Kim, Jung Min, Kim, Sang Yong, Kim, Seok-Mo, Lim, Jin Hong, Kim, Min Ki, Fang, Sungsoon, Kim, Yonjung, Mills, Gordon B., Noh, Sung Hoon, Cheong, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893610/
https://www.ncbi.nlm.nih.gov/pubmed/36726166
http://dx.doi.org/10.1186/s12916-023-02727-8