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Apoptotic tumor cell-derived microparticles loading Napabucasin inhibit CSCs and synergistic immune therapy

BACKGROUND: Cancer stem cells (CSCs) are crucial for the growth, metastasis, drug resistance, recurrence, and spread of tumors. Napabucasin (NAP) could effectively inhibit CSC, but its mechanism has not been fully explained. Additionally, NAP also has the drawbacks of poor water solubility and low u...

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Detalles Bibliográficos
Autores principales: Jing, Boping, Guo, Feng, An, Rui, Gao, Yu, Li, Yuman, Xie, Yuji, Wang, Jing, Chen, Yihan, Li, He, Gao, Tang, Jin, Qiaofeng, Zhang, Li, Xie, Mingxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893668/
https://www.ncbi.nlm.nih.gov/pubmed/36732759
http://dx.doi.org/10.1186/s12951-023-01792-8