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The maturation of iPS cell-derived brain microvascular endothelial cells by inducible-SOX18 expression

BACKGROUND: Brain microvascular endothelial cells (BMECs) play a major role in the blood–brain barrier (BBB), and are critical for establishing an in vitro BBB model. Currently, iPSC-derived BMECs (iBMECs) have been used to construct in vitro BBB models with physiological barrier functions, such as...

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Detalles Bibliográficos
Autores principales: Zhang, Hongyan, Yamaguchi, Tomoko, Kawabata, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9893670/
https://www.ncbi.nlm.nih.gov/pubmed/36732767
http://dx.doi.org/10.1186/s12987-023-00408-5